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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRMT3 All Species: 22.42
Human Site: S157 Identified Species: 41.11
UniProt: O60678 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60678 NP_005779.1 531 59903 S157 N G L S E N T S V V E K L K H
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001092890 531 59784 S157 N G L S E N T S V V E K L K C
Dog Lupus familis XP_534089 541 60618 S167 N G L N E N T S V V E K L K H
Cat Felis silvestris
Mouse Mus musculus Q922H1 532 59884 S155 N G L S E S A S V V E K L K H
Rat Rattus norvegicus O70467 528 59401 S155 N G L S E N T S A V E K L K L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505718 571 63850 S197 N G L S D N T S V L E R L K H
Chicken Gallus gallus XP_420907 526 59430 V153 N G L N D T T V L L K Q L K H
Frog Xenopus laevis Q8AV13 369 42306 R23 L A N G M S L R T P I E D V N
Zebra Danio Brachydanio rerio Q5RGQ2 419 48204 H73 P H P P H T P H V S A L S A C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396035 525 60169 T159 H F A E L Q R T I Q T L R A Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001192186 519 58632 E155 D G I S E S D E T V T I P A K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O82210 366 41153 H20 E T Q T T K L H F E D A D E S
Baker's Yeast Sacchar. cerevisiae P38074 348 39768
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 94.1 90.9 N.A. 89.8 89.2 N.A. 78.8 70.8 35.4 35.7 N.A. N.A. 42.5 N.A. 45
Protein Similarity: 100 N.A. 96.8 95.1 N.A. 93.9 93.9 N.A. 85.9 83.2 49.1 52.3 N.A. N.A. 62.5 N.A. 63.6
P-Site Identity: 100 N.A. 93.3 93.3 N.A. 86.6 86.6 N.A. 80 46.6 0 6.6 N.A. N.A. 0 N.A. 26.6
P-Site Similarity: 100 N.A. 93.3 100 N.A. 93.3 86.6 N.A. 100 86.6 20 6.6 N.A. N.A. 20 N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. 33.1 31.2 N.A.
Protein Similarity: N.A. N.A. N.A. 48.2 43.3 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 0 0 0 8 0 8 0 8 8 0 24 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16 % C
% Asp: 8 0 0 0 16 0 8 0 0 0 8 0 16 0 0 % D
% Glu: 8 0 0 8 47 0 0 8 0 8 47 8 0 8 0 % E
% Phe: 0 8 0 0 0 0 0 0 8 0 0 0 0 0 0 % F
% Gly: 0 62 0 8 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 8 8 0 0 8 0 0 16 0 0 0 0 0 0 39 % H
% Ile: 0 0 8 0 0 0 0 0 8 0 8 8 0 0 0 % I
% Lys: 0 0 0 0 0 8 0 0 0 0 8 39 0 54 8 % K
% Leu: 8 0 54 0 8 0 16 0 8 16 0 16 54 0 8 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 54 0 8 16 0 39 0 0 0 0 0 0 0 0 8 % N
% Pro: 8 0 8 8 0 0 8 0 0 8 0 0 8 0 0 % P
% Gln: 0 0 8 0 0 8 0 0 0 8 0 8 0 0 8 % Q
% Arg: 0 0 0 0 0 0 8 8 0 0 0 8 8 0 0 % R
% Ser: 0 0 0 47 0 24 0 47 0 8 0 0 8 0 8 % S
% Thr: 0 8 0 8 8 16 47 8 16 0 16 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 8 47 47 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _